PDF DatasheetHuman CXCL2 / MIP-2 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CXCL2 / MIP-2 based upon sequence from Human
Host: QP1016 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1016.
Bioactivity Data: Human CXCL2 / MIP-2 induces Human neutrophil chemotaxis (significanty different from control at Human CXCL2 / MIP-2 concentrations greater than 10 ng/ml)
Monomer or Dimer: Monomer
Amino Acid Sequence: APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human CXCL2 / MIP-2 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CXCL2 / MIP-2 Protein General Information | |
|---|---|
| Alternate Names | |
| CXCL2, MIP-2, CINC-2a, Scyb2, Gro2, GROb, Mgsa-b, Scyb, MIP-2, MIP-2a, Mip2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL2 |
| Entrez Gene ID | 2920 |
| Ensemble Gene ID | ENSG00000081041 |
| RefSeq Protein Accession(s) | NP_002080.1 |
| RefSeq mRNA Accession(s) | NM_002089.3 |
| UniProt ID(s) | P19875 |
| UniGene ID(s) | Hs.75765 |
| HGNC ID(s) | HGNC:4603 |
| COSMIC ID Link(s) | CXCL2 |
| KEGG Gene ID(s) | hsa:2920 |
| PharmGKB ID(s) | PA35051 |
| General Description of Recombinant Human CXCL2 / MIP-2 Protein . | |
| Growth regulated protein beta (GRO-beta), also known as CXCL2, is a chemokine that is secreted by macrophages, neutrophils, and monocytes at sites of inflammation. GRO-beta functions as a chemoattractant for leukocytes and hematopoietic stem cells. GRO-beta activity is mediated through binding the G-protein-coupled chemokine receptor CXCR2. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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