PDF DatasheetHuman FGF10 / KGF2 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant FGF10 / KGF2 based upon sequence from: Human
Host: QP5311 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5311.
Bioactivity Data: 4MBr-5 cell proliferation is significantly induced by less than 200 ng/ml of human FGF10 or activity measured must be greater than 5.0 x 10^3 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MLGQDMVSPE ATNSSSSSF S SPSSAGRH VR SYNHLQG DVR WRKLFS FTKY FLKIE KNGKV SGTK KENCPY SIL EITSVEIGVV AVKAINS NY YLAMNKKG K LYGSKEFNN DCKLKERIEE NGYNTYASF N WQHNGRQM YV ALNGKGA PRR GQKTRR KNTS AHFLP MVVHS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human FGF10 / KGF2 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human FGF10 / KGF2 Protein General Information | |
|---|---|
| Alternate Names | |
| FGF10, KGF2 Protein | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FGF10 |
| Entrez Gene ID | 2255 |
| Ensemble Gene ID | ENSG00000070193 |
| RefSeq Protein Accession(s) | NP_004456.1 |
| RefSeq mRNA Accession(s) | NM_004465.1, XM_005248264.3 |
| UniProt ID(s) | O15520 |
| UniGene ID(s) | Hs.248049 |
| HGNC ID(s) | HGNC:3666 |
| COSMIC ID Link(s) | FGF10 |
| KEGG Gene ID(s) | hsa:2255 |
| PharmGKB ID(s) | PA28106 |
| General Description of Recombinant Human FGF10 / KGF2 Protein . | |
| Fibroblast growth factor 10 (FGF10) is a growth factor that is important during embryonic development, especially during lung, limb, brain, heart, and kidney morphogenesis. FGF10 is expressed in mesenchymal cells and facilitates epithelial-mesenchymal signaling through binding the epithelially expressed FGF receptor 2b (FGFR2b). FGF10 also functions as a mitogen for keratinizing epidermal cells, and induces the migration and invasion of cancer cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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