PDF DatasheetHuman FGF22 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant FGF22 based upon sequence from: Human
Host: QP5374 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5374.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: MTPSASRGPR SYPHLEGDV R WRRLFSST HF FLRVDPG GRV QGTRWR HGQD SILEI RSVHV GVVV IKAVSS GFY VAMNRRG RL YGSRLYTVDC RFRERIEE N GHNTYASQR WRRRGQPMFL ALDRRGGPR P GGRTRRYH LS AHFLPVL VS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human FGF22 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human FGF22 Protein General Information | |
|---|---|
| Alternate Names | |
| FGF22, Fibroblast Growth Factor 22 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FGF22 |
| Entrez Gene ID | 27006 |
| Ensemble Gene ID | ENSG00000070388 |
| RefSeq Protein Accession(s) | NP_065688.1 |
| RefSeq mRNA Accession(s) | NM_020637.1 |
| UniProt ID(s) | Q9HCT0 |
| UniGene ID(s) | Hs.248087 |
| HGNC ID(s) | HGNC:3679 |
| COSMIC ID Link(s) | FGF22 |
| KEGG Gene ID(s) | hsa:27006 |
| PharmGKB ID(s) | PA28118 |
| General Description of Recombinant Human FGF22 Protein . | |
| Fibroblast growth factor 22 (FGF22) is a mediator of synaptogenesis in the adult nervous system and functions to regulate synapse formation and maturation. FGF22 is expressed in the inner hair cell and functions to maintain ribbon synapse number to protect functional hearing. In the hippocampus, FGF22 promotes excitatory synapse formation through binding the FGFR2b and FGFR1b receptors. FGF22 is also required for axonal circuit remodeling after spinal cord injury. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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