PDF DatasheetHuman FGF4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant FGF4 based upon sequence from: Human
Host: QP5343 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5343.
Bioactivity Data: Recombinant human FGF-4 induced 3T3 cell proliferation was measured at varying concentrations. Bioactivity was confirmed and an ED50 of approximately 3 ng/ml was measured.
Monomer or Dimer: Monomer
Amino Acid Sequence: MAPTAPNGTL EAELERRWES LVALSLARLP VAAQPKEAAV QSGAGDYLLG IKRLRRLYCN VGIGFHLQAL PDGRIGGAHA DTRDSLLELS PVERGVVSIF GVASRFFVAM SSKGKLYGSP FFTDECTFKE ILLPNNYNAY ESYKYPGMFI ALSKNGKTKK GNRVSPTMKV THFLPRL
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human FGF4 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 75mM sodium chloride, 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human FGF4 Protein General Information | |
|---|---|
| Alternate Names | |
| HST, KFGF, HST-1, HSTF1, K-FGF, HBGF-4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FGF4 |
| Entrez Gene ID | 2249 |
| Ensemble Gene ID | ENSG00000075388 |
| RefSeq Protein Accession(s) | NP_001998.1 |
| RefSeq mRNA Accession(s) | NM_002007.2, XM_005273847.1 |
| UniProt ID(s) | P08620 |
| UniGene ID(s) | Hs.1755 |
| HGNC ID(s) | HGNC:3682 |
| COSMIC ID Link(s) | FGF4 |
| KEGG Gene ID(s) | hsa:2249 |
| PharmGKB ID(s) | PA28121 |
| General Description of Recombinant Human FGF4 Protein . | |
| Fibroblast growth factor 4 (FGF4) is a secreted growth factor that is predominantly expressed during bone morphogenesis and embryonic limb development. FGF4 is an important growth regulator for stem cells, fibroblasts, and endothelial cells. FGF4 contains a single N-linked glycosylation signal. However, in-vitro studies suggest that unglycosylated FGF4 is cleaved into 13 kDa and 15 kDa truncated proteins that have greater biological activity than the wild type 19 kDa FGF4 protein. Human FGF4 shares high homology and is cross-reactive with mouse FGF4. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.