PDF DatasheetHuman FLT3L / Flt3 ligand Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant FLT3L / Flt3 ligand based upon sequence from: Human
Host: QP5327 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5327.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 10 ng/mL in the OCI-AML5 cell proliferation assay. The bioactivity acceptance criteria is set at 1 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human FLT3L / Flt3 ligand Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human FLT3L / Flt3 ligand Protein General Information | |
|---|---|
| Alternate Names | |
| FLT3L, Flt3 ligand, Flt3lg, Ly72L | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FLT3LG |
| Entrez Gene ID | 2323 |
| Ensemble Gene ID | ENSG00000090554 |
| RefSeq Protein Accession(s) | NP_001191431.1 |
| RefSeq mRNA Accession(s) | NM_001204502.1, NM_001204503.1, NM_001278637.1, NM_001278638.1, NM_001459.3, XM_011526682.2 |
| UniProt ID(s) | P49771 |
| UniGene ID(s) | Hs.428 |
| HGNC ID(s) | HGNC:3766 |
| COSMIC ID Link(s) | FLT3LG |
| KEGG Gene ID(s) | hsa:2323 |
| PharmGKB ID(s) | PA28182 |
| General Description of Recombinant Human FLT3L / Flt3 ligand Protein. | |
| Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7,) or in combination of IL-7 and interleukin 3 (IL-3). Human FLT-3 ligand is active on mouse cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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