Human GDF-8 / Myostatin / MSTN Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant GDF-8 / Myostatin / MSTN based upon sequence from: Human
Host: QP5265 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5265.
Bioactivity Data: Bioactivity of Myostatin Propeptide was confirmed by measuring inhibition of myostatin induced cytotoxicity in MCP-11 cells. Typical ED50 is around 1 ug/ml myostatin propeptide.
Monomer or Dimer: Monomer
Amino Acid Sequence: MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GDF-8 / Myostatin / MSTN Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
Recombinant Human GDF-8 / Myostatin / MSTN Protein General Information | |
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Alternate Names | |
GDF-8, Myostatin, MSTN, Cmpt, Gdf8 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | MSTN |
Entrez Gene ID | 2660 |
Ensemble Gene ID | ENSG00000138379 |
RefSeq Protein Accession(s) | NP_005250.1 |
RefSeq mRNA Accession(s) | NM_005259.2 |
UniProt ID(s) | O14793 |
UniGene ID(s) | Hs.41565 |
HGNC ID(s) | HGNC:4223 |
COSMIC ID Link(s) | MSTN |
KEGG Gene ID(s) | hsa:2660 |
PharmGKB ID(s) | PA162396253 |
General Description of Recombinant Human GDF-8 / Myostatin / MSTN Protein . | |
Myostatin (GDF-8), a member of the TGF-beta superfamily, is a potent and negative regulator of skeletal muscle mass. The recombinant myostatin propeptide binds and inhibits myostatin to enhance the repair and regeneration of injured muscle and bone. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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