PDF DatasheetHuman GH1 / Growth hormone 1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant GH1 / Growth hormone 1 based upon sequence from: Human
Host: QP5354 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5354.
Bioactivity Data: Human GH1 / Growth hormone 1 induces PDF 9D11 cell proliferation (typical ED50 is 1-15 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP TPSNREETQQ KSNLELLRIS LLLIQSWLEP VQFLRSVFAN SLVYGASDSN VYDLLKDLEE GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GH1 / Growth hormone 1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 20 mM sodium bicarbonate, pH 8.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human GH1 / Growth hormone 1 Protein General Information | |
|---|---|
| Alternate Names | |
| GH1, Growth hormone 1, GHN, GH, hGH-N, GH-N, IGHD1B, GHB5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GH1 |
| Entrez Gene ID | 2688 |
| Ensemble Gene ID | ENSG00000259384 |
| RefSeq Protein Accession(s) | NP_000506.2 |
| RefSeq mRNA Accession(s) | NM_000515.4, NM_022559.3, NM_022560.3 |
| UniProt ID(s) | P01241 |
| UniGene ID(s) | Hs.655229 |
| HGNC ID(s) | HGNC:4261 |
| COSMIC ID Link(s) | GH1 |
| KEGG Gene ID(s) | hsa:2688 |
| PharmGKB ID(s) | PA171 |
| General Description of Recombinant Human GH1 / Growth hormone 1 Protein . | |
| Growth hormone (GH) is an important mitogenic growth factor that is synthesized, stored, and secreted by somatotropic cells of the anterior pituitary gland. GH stimulates growth, cell reproduction, and cell regeneration. In children, GH deficiencies can cause short stature, growth failure, and delayed sexual maturity. Adult GH deficiency presents with reduced lean body mass, increased adiposity, reduced muscle strength, and ultimately premature mortality. GH replacement therapy is used to treat many growth disorders, including Turner syndrome, chronic renal failure, and PraderWilli syndrome. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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