PDF DatasheetHuman IL-27 beta / EBI3 subunit Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL-27 beta / EBI3 subunit based upon sequence from: Human
Host: QP5284 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5284.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: MRKGPPAALT LPRVQCRASR YPIAVDCSWT LPPAPNSTSP VSFIATYRLG MAARGHSWPC LQQTPTSTSC TITDVQLFSM APYVLNVTAV HPWGSSSSFV PFITEHIIKP DPPEGVRLSP LAERQLQVQW EPPGSWPFPE IFSLKYWIRY KRQGAARFHR VGPIEATSFI LRAVRPRARY YVQVAAQDLT DYGELSDWSL PATATMSLGK
Purity: Greater than 90 as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL-27 beta / EBI3 subunit Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 5.00 EUs/ug as determined by the LAL method.
Buffer: 0.1% Trifluoroacetic Acid (TFA) + 0.5% mannitol
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL-27 beta / EBI3 subunit Protein General Information | |
|---|---|
| Alternate Names | |
| IL27B, IL35B, IL-27B | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EBI3 |
| Entrez Gene ID | 10148 |
| Ensemble Gene ID | ENSG00000105246 |
| RefSeq Protein Accession(s) | NP_005746.2 |
| RefSeq mRNA Accession(s) | NM_005755.2, XM_011527619.2 |
| UniProt ID(s) | Q14213 |
| UniGene ID(s) | Hs.501452 |
| HGNC ID(s) | HGNC:3129 |
| COSMIC ID Link(s) | EBI3 |
| KEGG Gene ID(s) | hsa:10148 |
| PharmGKB ID(s) | PA27584 |
| General Description of Recombinant Human IL-27 beta / EBI3 subunit Protein . | |
| Epstein-Barr virus induced gene-3 (EBI3), is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form interleukin 27 (IL-27), and with p35 to form interleukin 35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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