PDF DatasheetHuman IL-35 Heterodimer Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL-35 Heterodimer based upon sequence from: Human
Host: QP5203 protein expressed in HEK 293 cells.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5203.
Bioactivity Data: Untested
Monomer or Dimer: Single chain dimer
Amino Acid Sequence: EBI3:RKGPP AALTLPRVQC RASRYPIAVD CSWTLPPAPN STSPVSFIAT YRLGMAARGH SWPCLQQTPT STSCTITDVQ LFSMAPYVLN VTAVHPWGSS SSFVPFITEH IIKPDPPEGV RLSPLAERQL QVQWEPPGSW PFPEIFSLKY WIRYKRQGAA RFHRVGPIEA TSFILRAVRP RARYYVQVAA QDLTDYGELS DWSLPATATM SLGKp35:RN LPVATPDPGM FPCLHHSQNL LRAVSNMLQK ARQTLEFYPC TSEEIDHEDI TKDKTSTVEA CLPLELTKNE SCLNSRETSF ITNGSCLASR KTSFMMALCL SSIYEDLKMY QVEFKTMNAK LLMDPKRQIF LDQNMLAVID ELMQALNFNS ETVPQKSSLE EPDFYKTKIK LCILLHAFRI RAVTIDRVMS YLNAS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL-35 Heterodimer Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 5.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 30 mM sodium chloride, pH7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL-35 Heterodimer Protein General Information | |
|---|---|
| Alternate Names | |
| IL35, IL-35 heterodimer | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL35 |
| UniProt ID(s) | Q14213; P29459 |
| General Description of Recombinant Human IL-35 Heterodimer Protein . | |
| Interleukin 35 (IL-35) is a member of the IL-12 cytokine family and is produced by regulatory T cells (Tregs). IL-35 is a heterodimeric cytokine that is comprised of the interleukin 12 subunit P35 (IL-12a) and the interleukin 27 subunit beta (IL-27b) chains. IL-35 binds the IL-12Rbeta2/gp130 hetero- and homodimers to activate STAT1 and STAT4 signaling. IL-35 functions as a suppressor of immune cell inflammatory responses. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.