PDF DatasheetHuman IL22 / Interleukin 22 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL22 / Interleukin 22 based upon sequence from Human
Host: QP1166 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1166.
Bioactivity Data: Human IL22 / Interleukin 22 induces pSTAT3 activation in HepG2 cells (detected via western blot at less than 5 ng/ml)
Monomer or Dimer: Dimer
Amino Acid Sequence: MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human IL22 / Interleukin 22 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium citrate, pH 3.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL22 / Interleukin 22 Protein General Information | |
|---|---|
| Alternate Names | |
| IL22, IL-22, Interleukin 22, TIFIL-23, IL-D110, ILTIF, IL-21, IL-22, zcyto18, IL-TIF, TIFa | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL22 |
| Entrez Gene ID | 50616 |
| Ensemble Gene ID | ENSG00000127318 |
| RefSeq Protein Accession(s) | NP_065386.1 |
| RefSeq mRNA Accession(s) | NM_020525.4 |
| UniProt ID(s) | Q9GZX6 |
| UniGene ID(s) | Hs.287369 |
| HGNC ID(s) | HGNC:14900 |
| COSMIC ID Link(s) | IL22 |
| KEGG Gene ID(s) | hsa:50616 |
| PharmGKB ID(s) | PA29822 |
| General Description of Recombinant Human IL22 / Interleukin 22 Protein . | |
| Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10Rbeta chains. IL-22 is a potent mediator of cellular inflammatory responses. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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