PDF DatasheetHuman IL33 / Interleukin-33 / NF-HEV Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL33 / Interleukin-33 / NF-HEV based upon sequence from Human
Host: QP1168 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1168.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 500 pg/mL in the D10S cell proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^6 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NESGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSET
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human IL33 / Interleukin-33 / NF-HEV Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL33 / Interleukin-33 / NF-HEV Protein General Information | |
|---|---|
| Alternate Names | |
| IL33, Interleukin-33, NF-HEV Protein, NF-HEV, C9orf26, DVS27, IL1F11, NFEHEV | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL33 |
| Entrez Gene ID | 90865 |
| Ensemble Gene ID | ENSG00000137033 |
| RefSeq Protein Accession(s) | NP_001186569.1 |
| RefSeq mRNA Accession(s) | NM_001199640.1, NM_001199641.1, NM_001314044.1, NM_001314045.1, NM_001314046.1, NM_001314047.1, NM_001314048.1, NM_033439.3 |
| UniProt ID(s) | O95760 |
| UniGene ID(s) | Hs.731660 |
| HGNC ID(s) | HGNC:16028 |
| COSMIC ID Link(s) | IL33 |
| KEGG Gene ID(s) | hsa:90865 |
| PharmGKB ID(s) | PA162392005 |
| General Description of Recombinant Human IL33 / Interleukin-33 / NF-HEV Protein. | |
| Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-?B and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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