PDF DatasheetHuman IL6 / Interleukin-6 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL6 / Interleukin-6 based upon sequence from: Human
Host: E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5239.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 250 pg/mL in the 7TD1 cell proliferation assay. The bioactivity acceptance criteria is set at 4 x 10^6 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL6 / Interleukin-6 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL6 / Interleukin-6 Protein (Animal Free) General Information | |
|---|---|
| Alternate Names | |
| IL6, Interleukin-6 Protein, BSF2, IL-6, HSF, BSF-2, CDF, HGF, IFN-beta-2, IFNB2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL6 |
| Entrez Gene ID | 3569 |
| Ensemble Gene ID | ENSG00000136244 |
| RefSeq Protein Accession(s) | NP_000591.1 |
| RefSeq mRNA Accession(s) | NM_000600.4, XM_011515390.2 |
| UniProt ID(s) | P05231 |
| UniGene ID(s) | Hs.654458 |
| HGNC ID(s) | HGNC:6018 |
| COSMIC ID Link(s) | IL6 |
| KEGG Gene ID(s) | hsa:3569 |
| PharmGKB ID(s) | PA198 |
| General Description of Recombinant Human IL6 / Interleukin-6 Protein (Animal Free). | |
| Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains. Human IL-6 is active on mouse and rat cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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