PDF DatasheetHuman IL7 / Interleukin 7 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL7 / Interleukin 7 based upon sequence from Human
Host: QP1180 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1180.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 1 ng/mL in the Mouse 2E8 cell proliferation assay. The bioactivity acceptance criteria is set at 1 x 10^6 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human IL7 / Interleukin 7 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM Aceitic acid
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL7 / Interleukin 7 Protein General Information | |
|---|---|
| Alternate Names | |
| IL7, Interleukin 7 Protein, Il-7, A630026I06Rik, hlb368 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL7 |
| Entrez Gene ID | 3574 |
| Ensemble Gene ID | ENSG00000104432 |
| RefSeq Protein Accession(s) | NP_000871.1 |
| RefSeq mRNA Accession(s) | NM_000880.3, NM_001199886.1, NM_001199887.1, NM_001199888.1 |
| UniProt ID(s) | P13232 |
| UniGene ID(s) | Hs.591873 |
| HGNC ID(s) | HGNC:6023 |
| COSMIC ID Link(s) | IL7 |
| KEGG Gene ID(s) | hsa:3574 |
| PharmGKB ID(s) | PA29839 |
| General Description of Recombinant Human IL7 / Interleukin 7 Protein. | |
| Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin 7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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