PDF DatasheetHuman Interferon alpha 2a Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Interferon alpha 2a based upon sequence from: Human
Host: QP5364 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5364.
Bioactivity Data: BioActivity: Shows bioactivity in the Viral CPE assay using EMC virus on A549 cells assay. The bioactivity acceptance criteria is set at 2.0 x 10^8 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MCDLPQTHSL GSRRTLMLLA QMRKISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Interferon alpha 2a Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human Interferon alpha 2a Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Entrez Gene ID | 3440 |
| Ensemble Gene ID | ENSG00000188379 |
| RefSeq Protein Accession(s) | NP_000596.2 |
| RefSeq mRNA Accession(s) | NM_000605.3 |
| UniProt ID(s) | P01563 |
| UniGene ID(s) | Hs.211575 |
| HGNC ID(s) | HGNC:5423 |
| KEGG Gene ID(s) | hsa:3440 |
| PharmGKB ID(s) | PA29662 |
| General Description of Recombinant Human Interferon alpha 2a Protein. | |
| Interferon-alpha 2a (IFN-?2a) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-?2a. IFN-? proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-?2a variant differs from IFN-?2b by one amino acid. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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