PDF DatasheetHuman MIP-3 beta / CCL19 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant MIP-3 beta / CCL19 based upon sequence from: Human
Host: QP5258 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5258.
Bioactivity Data: Human MIP-3 beta / CCL19 induces Primary human T cell chemotaxis.
Monomer or Dimer: Monomer
Amino Acid Sequence: GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MIP-3 beta / CCL19 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human MIP-3 beta / CCL19 Protein General Information | |
|---|---|
| Alternate Names | |
| ELC, CKb11, MIP3B, MIP-3b, SCYA19 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL19 |
| Entrez Gene ID | 6363 |
| Ensemble Gene ID | ENSG00000172724 |
| RefSeq Protein Accession(s) | NP_006265.1 |
| RefSeq mRNA Accession(s) | NM_006274.2 |
| UniProt ID(s) | Q99731 |
| UniGene ID(s) | Hs.50002 |
| HGNC ID(s) | HGNC:10617 |
| COSMIC ID Link(s) | CCL19 |
| KEGG Gene ID(s) | hsa:6363 |
| PharmGKB ID(s) | PA35550 |
| General Description of Recombinant Human MIP-3 beta / CCL19 Protein . | |
| Macrophage inflammatory protein-3 beta (MIP-3-beta), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells. MIP-3-beta signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation. MIP-3-beta also functions during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs. Human MIP-3-beta shows activity on mouse cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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