PDF DatasheetHuman Resistin / ADSF / RETN Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Resistin / ADSF / RETN based upon sequence from: Human
Host: QP5236 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5236.
Bioactivity Data: Human Resistin / ADSF / RETN induces ERK phosphorylation and activity (pERK) in SH-SY5Y cells via western blot (significanty different from control at Human Resistin / ADSF / RETN concentrations greater than 100 ng/ml).
Activity was further confirmed by measuring IL-8 production in human PBMCs (typical ED50 is less than 500 ng/ml).
Activity was further confirmed by measuring IL-8 production in human PBMCs (typical ED50 is less than 500 ng/ml).
Monomer or Dimer: Dimer
Amino Acid Sequence: MSSKTLCSME EAINERIQEV AGSLIFRAIS SIGLECQSVT SRGDLATCPR GFAVTGCTCG SACGSWDVRA ETTCHCQCAG MDWTGARCCR VQP
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Resistin / ADSF / RETN Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human Resistin / ADSF / RETN Protein General Information | |
|---|---|
| Alternate Names | |
| Resistin, ADSF, RETN, XCP1, RSTN, ADSF, RETN1, FIZZ3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RETN |
| Entrez Gene ID | 56729 |
| Ensemble Gene ID | ENSG00000104918 |
| RefSeq Protein Accession(s) | NP_001180303.1 |
| RefSeq mRNA Accession(s) | NM_001193374.1, NM_020415.3 |
| UniProt ID(s) | Q9HD89 |
| UniGene ID(s) | Hs.283091 |
| HGNC ID(s) | HGNC:20389 |
| COSMIC ID Link(s) | RETN |
| KEGG Gene ID(s) | hsa:56729 |
| PharmGKB ID(s) | PA422 |
| General Description of Recombinant Human Resistin / ADSF / RETN Protein . | |
| Resistin is a peptide hormone belonging to a class of cysteine-rich secreted proteins, termed the resistin-like molecules (RELM) family. Resistin is produced by macrophages and functions during insulin sensitivity and inflammatory processes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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