PDF DatasheetHuman SHH / Sonic hedgehog Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant SHH / Sonic hedgehog based upon sequence from: Human
Host: QP5292 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5292.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 5 ug/mL in the CCL-226 cell proliferation assay. The bioactivity acceptance criteria is set at 200 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MIIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKISRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRALDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human SHH / Sonic hedgehog Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human SHH / Sonic hedgehog Protein General Information | |
|---|---|
| Alternate Names | |
| SHH, Sonic hedgehog, HPE3, MCOPCB5, SMMCI, HLP3, TPTPS, HHG1, TPT | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SHH |
| Entrez Gene ID | 6469 |
| Ensemble Gene ID | ENSG00000164690 |
| RefSeq Protein Accession(s) | NP_000184.1 |
| RefSeq mRNA Accession(s) | NM_000193.3 |
| UniProt ID(s) | Q15465 |
| UniGene ID(s) | Hs.164537 |
| HGNC ID(s) | HGNC:10848 |
| COSMIC ID Link(s) | SHH |
| KEGG Gene ID(s) | hsa:6469 |
| PharmGKB ID(s) | PA35752 |
| General Description of Recombinant Human SHH / Sonic hedgehog Protein. | |
| Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.