PDF DatasheetHuman, Mouse and Rat Anti-Mesothelin (Mesothelial Marker) Antibody Product Attributes
Species: Human, Mouse and Rat
Tested Applications: IHC.
Clonality: Monoclonal
Anti-Mesothelin (Mesothelial Marker) Antibody Clone: MSLN/2131
Clone MSLN/2131 Host and Isotype: Mouse IgG2b, kappa
Anti-Human, Mouse and Rat Mesothelin (Mesothelial Marker) Positive Control Sample: CAPAN-2 or HeLa cells. Lung Mesothelioma.
Cellular Localization of Antibody MSLN/2131 Staining: Cell Surface and Secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment (apprx. aa 273-407) of human Mesothelin (MSLN) protein (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
Mesothelin (Mesothelial Marker) Previously Observed Antibody Staining Patterns
| Mesothelin (Mesothelial Marker) General Information | |
|---|---|
| Alternate Names | |
| CAK1; Megakaryocyte potentiating factor; Mesothelin; MSLN; SMR; SMRP | |
| Molecular Weight | |
| 40kDa (Mature form); 69kDa (Precursor) | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 10232 |
| Entrez Gene ID | MSLN |
| UniProt ID(s) | Q13421 |
| UniGene ID(s) | Hs408488 |
| COSMIC ID Link(s) | MSLN |
| KEGG Gene ID(s) | hsa:10232 |
| General Description of Mesothelin (Mesothelial Marker). | |
| Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma. | |
Limitations and Warranty
enQuire Bio’s product, Mesothelin (Mesothelial Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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