PDF DatasheetMouse CXCL10 / Crg-2 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CXCL10 / Crg-2 based upon sequence from: Mouse
Host: QP5448 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5448.
Bioactivity Data: Mouse CXCL10 / Crg-2 induces Primary human T cell chemotaxis (significanty different from control at Mouse CXCL10 / Crg-2 concentrations greater than 5 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse CXCL10 / Crg-2 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse CXCL10 / Crg-2 Protein General Information | |
|---|---|
| Alternate Names | |
| CXCL10, Crg-2, IP10, mob-1, IP-10, CRG-2, gIP-10, INP10, Scyb10, C7, Ifi10 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL10 |
| Entrez Gene ID | 15945 |
| Ensemble Gene ID | ENSMUSG00000034855 |
| RefSeq Protein Accession(s) | NP_067249.1 |
| RefSeq mRNA Accession(s) | NM_021274.2 |
| UniProt ID(s) | P17515 |
| UniGene ID(s) | Mm.877 |
| COSMIC ID Link(s) | CXCL10 |
| KEGG Gene ID(s) | mmu:15945 |
| General Description of Recombinant Mouse CXCL10 / Crg-2 Protein . | |
| Interferon gamma-induced protein 10 (IP-10), or CXCL10, is a chemokine secreted by monocytes, endothelial cells and fibroblasts in response to interferon gamma (IFN?). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and natural killer (NK) cells that express the G protein-coupled receptor CXCR3. IP-10 is an important factor in autoimmune diseases such as Hashimoto’s thyroiditis, Graves’ disease, and Type 1 diabetes mellitus. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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