PDF DatasheetMouse G-CSF / CSF3 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant G-CSF / CSF3 based upon sequence from: Mouse
Host: QP5415 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5415.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 50 pg/mL in the NFS-60 cell proliferation assay. The bioactivity acceptance criteria is set at 2 x 10^7 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse G-CSF / CSF3 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium citrate, pH 3.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse G-CSF / CSF3 Protein General Information | |
|---|---|
| Alternate Names | |
| G-CSF, CSF3, CSF3OS, C17orf33, GCSF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CSF3 |
| Entrez Gene ID | 12985 |
| Ensemble Gene ID | ENSMUSG00000038067 |
| RefSeq Protein Accession(s) | NP_034101.1 |
| RefSeq mRNA Accession(s) | NM_009971.1 |
| UniProt ID(s) | P09920 |
| UniGene ID(s) | Mm.1238 |
| COSMIC ID Link(s) | CSF3 |
| KEGG Gene ID(s) | mmu:12985 |
| General Description of Recombinant Mouse G-CSF / CSF3 Protein. | |
| Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF?), interleukin 1 (IL-1), or interleukin 17 (IL-17). The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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