PDF DatasheetMouse IL-12AB Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL-12AB based upon sequence from: Mouse
Host: QP5204 protein expressed in HEK 293 cells.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5204.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 20 ng/mL in the Mouse primary T cell induced expression of CD25 assay. The bioactivity acceptance criteria is set at 5 x 10^4 units/mg.
Monomer or Dimer: Heterodimer
Amino Acid Sequence: p35:MRVIPV SGPARCLSQS RNLLKTTDDM VKTAREKLKH YSCTAEDIDH EDITRDQTST LKTCLPLELH KNESCLATRE TSSTTRGSCL PPQKTSLMMT LCLGSIYEDL KMYQTEFQAI NAALQNHNHQ QIILDKGMLV AIDELMQSLN HNGETLRQKP PVGEADPYRV KMKLCILLHA FSTRVVTINR VMGYLSSAp4 0:MWELEKDV YVVEVDWTPD APGETVNLTC DTPEEDDITW TSDQRHGVIG SGKTLTITVK EFLDAGQYTC HKGGETLSHS HLLLHKKENG IWSTEILKNF KNKTFLKCEA PNYSGRFTCS WLVQRNMDLK FNIKSSSSSP DSRAVTCGMA SLSAEKVTLD QRDYEKYSVS CQEDVTCPTA EETLPIELAL EARQQNKYEN YSTSFFIRDI IKPDPPKNLQ MKPLKNSQVE VSWEYPDSWS TPHSYFSLKF FVRIQRKKEK MKETEEGCNQ KGAFLVEKTS TEVQCKGGNV CVQAQDRYYN SSCSKWACVP CRVRS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse IL-12AB Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse IL-12AB Protein General Information | |
|---|---|
| Alternate Names | |
| IL12A, NKSF1, CLMF, IL-12A, P35, NFSK, NKSF1, IL12B, P40, IMD29, CLMF2, CLMF, IL-12B, IMD28, NKSF, NKSF2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL12 |
| Entrez Gene ID | 16160 |
| Ensemble Gene ID | ENSMUSG00000004296 |
| RefSeq Protein Accession(s) | NP_001290173.1 |
| RefSeq mRNA Accession(s) | NM_001303244.1 |
| UniProt ID(s) | P43432; P43431 |
| UniGene ID(s) | Mm.239707 |
| KEGG Gene ID(s) | mmu:16160 |
| General Description of Recombinant Mouse IL-12AB Protein. | |
| Interleukin 12 (IL-12) is an inducer of cell-mediated immunity and is produced by dendritic cells, macrophages, and B cells after antigen stimulation. IL-12 functions to promote naïve T cell differentiation into the type 1 T helper cell (Th1) lineage. IL-12 also stimulates the production of interferon gamma (IFN?) and tumor necrosis factor alpha (TNF?) from T cells and natural killer cells. Mouse IL-12 is active on human and mouse cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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