PDF DatasheetMouse IL-31 / IL31 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL-31 / IL31 based upon sequence from Mouse
Host: QP5477 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5477.
Bioactivity Data: Mouse IL-31 / IL31 induces IL-8 production in human PBMCs which was detected via ELISA (typical ED50 is ? 25 ng/ml)
Monomer or Dimer: Monomer
Amino Acid Sequence: MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse IL-31 / IL31 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse IL-31 / IL31 Protein General Information | |
|---|---|
| Alternate Names | |
| IL-31, IL31, 1700013B14Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL31 |
| Entrez Gene ID | 76399 |
| Ensemble Gene ID | ENSMUSG00000029437 |
| RefSeq Protein Accession(s) | NP_083870.1 |
| RefSeq mRNA Accession(s) | NM_029594.1, XM_006530498.1 |
| UniProt ID(s) | Q6EAL8 |
| UniGene ID(s) | Mm.75049 |
| COSMIC ID Link(s) | IL31 |
| KEGG Gene ID(s) | mmu:76399 |
| General Description of Recombinant Mouse IL-31 / IL31 Protein . | |
| Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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