PDF DatasheetMouse Il27 alpha Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Il27 alpha based upon sequence from Mouse
Host: QP5458 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5458.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: MALVALSQPR VQCHASRYPV AVDCSWTPLQ APNSTRSTSF IATYRLGVAT QQQSQPCLQR SPQASRCTIP DVHLFSTVPY MLNVTAVHPG GASSSLLAFV AERIIKPDPP EGVRLRTAGQ RLQVLWHPPA SWPFPDIFSL KYRLRYRRRG ASHFRQVGPI EATTFTLRNS KPHAKYCIQV SAQDLTDYGK PSDWSLPGQV ESAPHKP
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse Il27 alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium bicarbonate, pH 8.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse Il27 alpha Protein (Animal Free) General Information | |
|---|---|
| Alternate Names | |
| p28, Il30, IL-27, IL-27p28 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL27Ra |
| Entrez Gene ID | 246779 |
| Ensemble Gene ID | ENSMUSG00000044701 |
| RefSeq Protein Accession(s) | NP_663611.1 |
| RefSeq mRNA Accession(s) | NM_145636.1 |
| UniProt ID(s) | Q8K3I6 |
| UniGene ID(s) | Mm.222632 |
| COSMIC ID Link(s) | IL27Ra |
| KEGG Gene ID(s) | mmu:246779 |
| General Description of Recombinant Mouse Il27 alpha Protein (Animal Free). | |
| The p28 subunit of interleukin 27 (IL-27), also known as interleukin 30 (IL-30), is a member of the interleukin 12 (IL-12) family of cytokines. p28 is a 28 kilodalton polypeptide that associates with the Epstein-Barr virus induced gene 3 (EBI3) to form the IL-27 cytokine heterodimer complex. IL-27 functions as a proinflammatory cytokine that induces immunomodulatory effects in naïve CD4+ T cells, mast cells, and monocytes. p28 can also form a complex with cytokine-like factor 1 (CLF), that is secreted by dendritic cells, to regulate natural killer (NK) and T cell function. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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