PDF DatasheetMouse IL5 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL5 based upon sequence from: Mouse
Host: QP5423 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5423.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 2 ng/mL in the TF-1 cell proliferation assay. The bioactivity acceptance criteria is set at 5 x 10^5 units/mg.
Monomer or Dimer: Dimer
Amino Acid Sequence: MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse IL5 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 20 mM sodium bicarbonate, pH 9.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse IL5 Protein General Information | |
|---|---|
| Alternate Names | |
| IL5, EDF, IL-5, TRF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL5 |
| Entrez Gene ID | 16191 |
| Ensemble Gene ID | ENSMUSG00000036117 |
| RefSeq Protein Accession(s) | NP_034688.1 |
| RefSeq mRNA Accession(s) | NM_010558.1 |
| UniProt ID(s) | P04401 |
| UniGene ID(s) | Mm.4461 |
| COSMIC ID Link(s) | IL5 |
| KEGG Gene ID(s) | mmu:16191 |
| General Description of Recombinant Mouse IL5 Protein. | |
| Interleukin 5 (IL-5) is a hematopoietic growth factor that is expressed in type 2 T helper (Th2) cells, mast cells, and eosinophils. IL-5 acts through the IL-5 receptor (IL-5R), stimulates B cell growth, and mediates eosinophil activation. IL-5 expression is regulated by the GATA binding protein 3 (GATA3) transcription factor. Human and mouse IL-5 show cross-reactivity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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