PDF DatasheetMouse RANKL / OPGL / TNFSF11 / CD254 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant RANKL / OPGL / TNFSF11 / CD254 based upon sequence from: Mouse
Host: QP5403 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5403.
Bioactivity Data: Mouse RANKL / OPGL / TNFSF11 / CD254 induces TNF-alpha production in RAW cells (typical ED50 is 50-75 ng/ml)
. Activity was further confirmed by measuring Osteoclast formation (significanty different from control at Mouse RANKL / OPGL / TNFSF11 / CD254 concentrations greater than 50 ng/ml).
. Activity was further confirmed by measuring Osteoclast formation (significanty different from control at Mouse RANKL / OPGL / TNFSF11 / CD254 concentrations greater than 50 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: MPAMMEGSWL DVAQRGKPEA QPFAHLTINA ASIPSGSHKV TLSSWYHDRG WAKISNMTLS NGKLRVNQDG FYYLYANICF RHHETSGSVP TDYLQLMVYV VKTSIKIPSS HNLMKGGSTK NWSGNSEFHF YSINVGGFFK LRAGEEISIQ VSNPSLLDPD QDATYFGAFK VQDID
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse RANKL / OPGL / TNFSF11 / CD254 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate and 20 mM sodium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse RANKL / OPGL / TNFSF11 / CD254 Protein (Animal Free) General Information | |
|---|---|
| Alternate Names | |
| RANKL, OPGL, TNFSF11, CD254, ODF, TNLG6B, sOdf, TRANCE, hRANKL2, OPGL, CD254, RANKL, OPTB2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFSF11 |
| Entrez Gene ID | 21943 |
| Ensemble Gene ID | ENSMUSG00000022015 |
| RefSeq Protein Accession(s) | NP_035743.2 |
| RefSeq mRNA Accession(s) | NM_011613.3 |
| UniProt ID(s) | O35235 |
| UniGene ID(s) | Mm.249221 |
| COSMIC ID Link(s) | TNFSF11 |
| KEGG Gene ID(s) | mmu:21943 |
| General Description of Recombinant Mouse RANKL / OPGL / TNFSF11 / CD254 Protein (Animal Free). | |
| Receptor activator of nuclear factor kappa-B Ligand (RANKL) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANKL plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANKL promotes dendritic cell maturation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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