PDF DatasheetMouse SHH / Sonic hedgehog Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant SHH / Sonic hedgehog based upon sequence from Mouse
Host: QP5463 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5463.
Bioactivity Data: Sonic Hedgehog ( SHH ) activity was confirmed in a CCL-226 cell proliferatin assay. See figure for results.
Monomer or Dimer: Monomer
Amino Acid Sequence: MIIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKITRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse SHH / Sonic hedgehog Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse SHH / Sonic hedgehog Protein General Information | |
|---|---|
| Alternate Names | |
| SHH, Sonic hedgehog, HPE3, MCOPCB5, SMMCI, HLP3, TPTPS, HHG1, TPT | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SHH |
| Entrez Gene ID | 20423 |
| Ensemble Gene ID | ENSMUSG00000002633 |
| RefSeq Protein Accession(s) | NP_033196.1 |
| RefSeq mRNA Accession(s) | NM_009170.3 |
| UniProt ID(s) | Q62226 |
| UniGene ID(s) | Mm.57202 |
| COSMIC ID Link(s) | SHH |
| KEGG Gene ID(s) | mmu:20423 |
| General Description of Recombinant Mouse SHH / Sonic hedgehog Protein . | |
| Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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