PDF DatasheetHuman Histidine–tRNA ligase, cytoplasmic Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histidine–tRNA ligase, cytoplasmic based upon sequence from: Human
Host: QP10038 protein expressed in Baculovirus.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histidine–tRNA ligase, cytoplasmic, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10038.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala2 – Gln504
Amino Acid Sequence: AERAALEELV KLQGERVRGL KQQKASAELI EEEVAKLLKL KAQLGPDESK QKFVLKTPKG TRDYSPRQMA VREKVFDVII RCFKRHGAEV IDTPVFELKE TLMGKYGEDS KLIYDLKDQG GELLSLRYDL TVPFARYLAM NKLTNIKRYH IAKVYRRDNP AMTRGRYREF YQCDFDIAGN FDPMIPDAEC LKIMCEILSS LQIGDFLVKV NDRRILDGMF AICGVSDSKF RTICSSVDKL DKVSWEEVKN EMVGEKGLAP EVADRIGDYV QQHGGVSLVE QLLQDPKLSQ NKQALEGLGD LKLLFEYLTL FGIDDKISFD LSLARGLDYY TGVIYEAVLL QTPAQAGEEP LGVGSVAAGG RYDGLVGMFD PKGRKVPCVG LSIGVERIFS IVEQRLEALE EKIRTTETQV LVASAQKKLL EERLKLVSEL WDAGIKAELL YKKNPKLLNQ LQYCEEAGIP LVAIIGEQEL KDGVIKLRSV TSREEVDVRR EDLVEEIKRR TGQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Histidine–tRNA ligase, cytoplasmic Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Histidine–tRNA ligase, cytoplasmic Protein General Information | |
|---|---|
| Alternate Names | |
| USH3B; HRS; CMT2W | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HARS |
| Entrez Gene ID | 3035 |
| Ensemble Gene ID | ENSG00000170445 |
| RefSeq Protein Accession(s) | NP_001244969.1 |
| RefSeq mRNA Accession(s) | NM_001258040.2, NM_001258041.2, NM_001258042.2, NM_002109.5 |
| UniProt ID(s) | P12081 |
| UniGene ID(s) | Hs.528050 |
| HGNC ID(s) | HGNC:4816 |
| COSMIC ID Link(s) | HARS |
| KEGG Gene ID(s) | hsa:3035 |
| PharmGKB ID(s) | PA29191 |
| General Description of Recombinant Human Histidine–tRNA ligase, cytoplasmic Protein. | |
| Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins.The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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