PDF DatasheetHuman MICA Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant MICA based upon sequence from: Human
Host: QP10172 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human MICA, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10172.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The specific activity is determined by binding MICA antibody in ELISA.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: EPHSLRYNLT VLSWDGSVQS GFLAEVHLDG QPFLRYDRQK CRAKPQGQWA EDVLGNKTWD RETRDLTGNG KDLRMTLAHI KDQKEGLHSL QEIRVCEIHE DNSTRSSQHF YYDGELFLSQ NLETEEWTVP QSSRAQTLAM NVRNFLKEDA MKTKTHYHAM HADCLQELRR YLESGVVLRR TVPPMVNVTR SEASEGNITV TCRASSFYPR NIILTWRQDG VSLSHDTQQW GDVLPDGNGT YQTWVATRIC RGEEQRFTCY MEHSGNHSTH PVPSGKVLVL QSHW
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human MICA Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 30 % Acetonitrile, 0.1% TFA, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MICA Protein General Information | |
|---|---|
| Alternate Names | |
| MICA; MIC-A; PERB11.1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MICA |
| Entrez Gene ID | 100507436 |
| Ensemble Gene ID | ENSG00000183214 |
| RefSeq Protein Accession(s) | NP_000238.1 |
| RefSeq mRNA Accession(s) | NM_000247.2 |
| UniProt ID(s) | Q29983 |
| UniGene ID(s) | Hs.130838 |
| HGNC ID(s) | HGNC:7090 |
| COSMIC ID Link(s) | MICA |
| KEGG Gene ID(s) | hsa:100507436 |
| PharmGKB ID(s) | PA30811 |
| General Description of Recombinant Human MICA Protein. | |
| Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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