PDF DatasheetHuman Trefoil factor 2 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Trefoil factor 2 based upon sequence from: Human
Host: QP10179 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Trefoil factor 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10179.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 × 105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Trefoil factor 2 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM PBS, pH 7.4, 150mM NaCl, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Trefoil factor 2 Protein General Information | |
|---|---|
| Alternate Names | |
| SP; SML1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TFF2 |
| Entrez Gene ID | 7032 |
| Ensemble Gene ID | ENSG00000160181 |
| RefSeq Protein Accession(s) | NP_005414.1 |
| RefSeq mRNA Accession(s) | NM_005423.4 |
| UniProt ID(s) | Q03403 |
| UniGene ID(s) | Hs.2979 |
| HGNC ID(s) | HGNC:11756 |
| COSMIC ID Link(s) | TFF2 |
| KEGG Gene ID(s) | hsa:7032 |
| PharmGKB ID(s) | PA36471 |
| General Description of Recombinant Human Trefoil factor 2 Protein. | |
| Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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