PDF DatasheetHuman CXCL4 / PF4 Protein Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CXCL4 / PF4 Protein based upon sequence from Human
Host: QP1018 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CXCL4 / PF4 Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP1018.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human fibroblasts is in a concentration of 1.0-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human CXCL4 / PF4 Protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CXCL4 / PF4 Protein Protein General Information | |
|---|---|
| Alternate Names | |
| CXCL4, PF4 Protein, SCYB4, CXCL4, PF-4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PF4 |
| Entrez Gene ID | 5196 |
| Ensemble Gene ID | ENSG00000163737 |
| RefSeq Protein Accession(s) | NP_002610.1 |
| RefSeq mRNA Accession(s) | NM_002619.3 |
| UniProt ID(s) | P02776 |
| UniGene ID(s) | Hs.81564 |
| HGNC ID(s) | HGNC:8861 |
| COSMIC ID Link(s) | PF4 |
| KEGG Gene ID(s) | hsa:5196 |
| PharmGKB ID(s) | PA33203 |
| General Description of Recombinant Human CXCL4 / PF4 Protein Protein. | |
| Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.