PDF DatasheetHuman Thymosin beta-4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Thymosin beta-4 based upon sequence from: Human
Host: QP10182 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Thymosin beta-4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10182.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5 – 10 ug/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Thymosin beta-4 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM PBS, pH 7.4, 150mM NaCl, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Thymosin beta-4 Protein General Information | |
|---|---|
| Alternate Names | |
| FX; TB4X; PTMB4; TMSB4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TMSB4X |
| Entrez Gene ID | 7114 |
| Ensemble Gene ID | ENSG00000205542 |
| RefSeq Protein Accession(s) | NP_066932.1 |
| RefSeq mRNA Accession(s) | NM_021109.3 |
| UniProt ID(s) | P62328 |
| UniGene ID(s) | Hs.437277 |
| HGNC ID(s) | HGNC:11881 |
| COSMIC ID Link(s) | TMSB4X |
| KEGG Gene ID(s) | hsa:7114 |
| PharmGKB ID(s) | PA36581 |
| General Description of Recombinant Human Thymosin beta-4 Protein. | |
| Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. ; Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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