PDF DatasheetHuman Melanoma-derived growth regulatory protein Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Melanoma-derived growth regulatory protein based upon sequence from: Human
Host: QP10187 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Melanoma-derived growth regulatory protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10187.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human A375 cell line is less than 5 ug/ml, corresponding to a specific activity of > 200 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: GPMPKLADRK LCADQECSHP ISMAVALQDY MAPDCRFLTI HRGQVVYVFS KLKGRGRLFW GGSVQGDYYG DLAARLGYFP SSIVREDQTL KPGKVDVKTD KWDFYCQ
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Melanoma-derived growth regulatory protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM PBS, pH 7.4, 150mM NaCl, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Melanoma-derived growth regulatory protein Protein General Information | |
|---|---|
| Alternate Names | |
| CD-RAP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MIA |
| Entrez Gene ID | 8190 |
| Ensemble Gene ID | ENSG00000261857 |
| RefSeq Protein Accession(s) | NP_001189482.1 |
| RefSeq mRNA Accession(s) | NM_001202553.1, NM_006533.3 |
| UniProt ID(s) | Q16674 |
| UniGene ID(s) | Hs.646364 |
| HGNC ID(s) | HGNC:7076 |
| COSMIC ID Link(s) | MIA |
| KEGG Gene ID(s) | hsa:8190 |
| PharmGKB ID(s) | PA30800 |
| General Description of Recombinant Human Melanoma-derived growth regulatory protein Protein. | |
| Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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