PDF DatasheetHuman Galectin-1 / LGALS1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Galectin-1 / LGALS1 based upon sequence from: Human
Host: QP10191 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Galectin-1 / LGALS1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10191.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.0-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Galectin-1 / LGALS1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM PBS, pH 7.4, 150mM NaCl, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Galectin-1 / LGALS1 Protein General Information | |
|---|---|
| Alternate Names | |
| Galectin-1; LGALS1; L14; Gal-1; galectin-1; Galbp; L-14.5; AA410090; Lect14 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LGALS1 |
| Entrez Gene ID | 3956 |
| Ensemble Gene ID | ENSG00000100097 |
| RefSeq Protein Accession(s) | NP_002296.1 |
| RefSeq mRNA Accession(s) | NM_002305.3 |
| UniProt ID(s) | P09382 |
| UniGene ID(s) | Hs.445351 |
| HGNC ID(s) | HGNC:6561 |
| COSMIC ID Link(s) | LGALS1 |
| KEGG Gene ID(s) | hsa:3956 |
| PharmGKB ID(s) | PA30337 |
| General Description of Recombinant Human Galectin-1 / LGALS1 Protein. | |
| May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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