PDF DatasheetHuman CCL16 / HCC-4 / NCC4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL16 / HCC-4 / NCC4 based upon sequence from: Human
Host: QP10202 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL16 / HCC-4 / NCC4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10202.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL16 / HCC-4 / NCC4 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL16 / HCC-4 / NCC4 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL16; HCC-4; NCC4; LEC; HCC-4; LCC-1; CKb12; SCYA16; SCYL4; LMC; Mtn-1; NCC-4; ILINCK; NCC4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL16 |
| Entrez Gene ID | 6360 |
| Ensemble Gene ID | ENSG00000275152 |
| RefSeq Protein Accession(s) | NP_004581.1 |
| RefSeq mRNA Accession(s) | NM_004590.3, XM_005258020.4 |
| UniProt ID(s) | O15467 |
| UniGene ID(s) | Hs.10458 |
| HGNC ID(s) | HGNC:10614 |
| KEGG Gene ID(s) | hsa:6360 |
| PharmGKB ID(s) | PA35547 |
| General Description of Recombinant Human CCL16 / HCC-4 / NCC4 Protein. | |
| Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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