PDF DatasheetHuman CXCL3 / GRO gamma Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CXCL3 / GRO gamma based upon sequence from: Human
Host: QP10207 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CXCL3 / GRO gamma, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10207.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CXCL3 / GRO gamma Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CXCL3 / GRO gamma Protein General Information | |
|---|---|
| Alternate Names | |
| CXCL3; GRO gamma; GRO3; MIP-2b; SCYB3; GROg; MIP2B; CINC-2b | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL3 |
| Entrez Gene ID | 2921 |
| Ensemble Gene ID | ENSG00000163734 |
| RefSeq Protein Accession(s) | NP_002081.2 |
| RefSeq mRNA Accession(s) | NM_002090.2 |
| UniProt ID(s) | P19876 |
| UniGene ID(s) | Hs.89690 |
| HGNC ID(s) | HGNC:4604 |
| COSMIC ID Link(s) | CXCL3 |
| KEGG Gene ID(s) | hsa:2921 |
| PharmGKB ID(s) | PA35052 |
| General Description of Recombinant Human CXCL3 / GRO gamma Protein. | |
| Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.