PDF DatasheetHuman C-X-C motif chemokine 6 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant C-X-C motif chemokine 6 based upon sequence from: Human
Host: QP10211 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human C-X-C motif chemokine 6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10211.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human C-X-C motif chemokine 6 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human C-X-C motif chemokine 6 Protein General Information | |
|---|---|
| Alternate Names | |
| SCYB6; CKA-3; GCP2; GCP-2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL6 |
| Entrez Gene ID | 6372 |
| Ensemble Gene ID | ENSG00000124875 |
| RefSeq Protein Accession(s) | NP_002984.1 |
| RefSeq mRNA Accession(s) | NM_002993.3 |
| UniProt ID(s) | P80162 |
| HGNC ID(s) | HGNC:10643 |
| COSMIC ID Link(s) | CXCL6 |
| KEGG Gene ID(s) | hsa:6372 |
| PharmGKB ID(s) | PA35574 |
| General Description of Recombinant Human C-X-C motif chemokine 6 Protein. | |
| Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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