PDF DatasheetHuman C-X-C motif chemokine 17 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant C-X-C motif chemokine 17 based upon sequence from: Human
Host: QP10220 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human C-X-C motif chemokine 17, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10220.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0 ug/ml, corresponding to a specific activity of > 200 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: SSLNPGVARG HRDRGQASRR WLQEGGQECE CKDWFLRAPR RKFMTVSGLP KKQCPCDHFK GNVKKTRHQR HHRKPNKHSR ACQQFLKQCQ LRSFALPL
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human C-X-C motif chemokine 17 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human C-X-C motif chemokine 17 Protein General Information | |
|---|---|
| Alternate Names | |
| DMC; VCC1; UNQ473; VCC-1; Dcip1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL17 |
| Entrez Gene ID | 284340 |
| Ensemble Gene ID | ENSG00000189377 |
| RefSeq Protein Accession(s) | NP_940879.1 |
| RefSeq mRNA Accession(s) | NM_198477.2 |
| UniProt ID(s) | Q6UXB2 |
| HGNC ID(s) | HGNC:19232 |
| COSMIC ID Link(s) | CXCL17 |
| KEGG Gene ID(s) | hsa:284340 |
| PharmGKB ID(s) | PA162383045 |
| General Description of Recombinant Human C-X-C motif chemokine 17 Protein. | |
| Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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