PDF DatasheetHuman CCL2 / MCP-1 / MCP1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL2 / MCP-1 / MCP1 based upon sequence from: Human
Host: QP10224 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL2 / MCP-1 / MCP1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10224.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL2 / MCP-1 / MCP1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL2 / MCP-1 / MCP1 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL2; MCP-1; MCP1; Scya2; JE; HC11; MCP1; AI323594; MCAF; MCP-1; Sigje; SMC-CF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL2 |
| Entrez Gene ID | 6347 |
| Ensemble Gene ID | ENSG00000108691 |
| RefSeq Protein Accession(s) | NP_002973.1 |
| RefSeq mRNA Accession(s) | NM_002982.3 |
| UniProt ID(s) | P13500 |
| UniGene ID(s) | Hs.303649 |
| HGNC ID(s) | HGNC:10618 |
| COSMIC ID Link(s) | CCL2 |
| KEGG Gene ID(s) | hsa:6347 |
| PharmGKB ID(s) | PA130413151 |
| General Description of Recombinant Human CCL2 / MCP-1 / MCP1 Protein. | |
| Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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