PDF DatasheetHuman CCL23 / MIP 3 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL23 / MIP 3 based upon sequence from: Human
Host: QP10238 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL23 / MIP 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10238.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-50 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL23 / MIP 3 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL23 / MIP 3 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL23; MIP 3; Ckb-8; CKb8; Ckb-8-1; hmrp-2a; MIP-3; MIP3; CK-BETA-8; MPIF-1; SCYA23 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL23 |
| Entrez Gene ID | 6368 |
| Ensemble Gene ID | ENSG00000276114 |
| RefSeq Protein Accession(s) | NP_005055.3 |
| RefSeq mRNA Accession(s) | NM_005064.5, NM_145898.3 |
| UniProt ID(s) | P55773 |
| HGNC ID(s) | HGNC:10622 |
| KEGG Gene ID(s) | hsa:6368 |
| PharmGKB ID(s) | PA35554 |
| General Description of Recombinant Human CCL23 / MIP 3 Protein. | |
| Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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