PDF DatasheetHuman CCL24 / Eotaxin-2 / MPIF-2 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL24 / Eotaxin-2 / MPIF-2 based upon sequence from: Human
Host: QP10239 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL24 / Eotaxin-2 / MPIF-2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10239.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration of 50-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKAGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL24 / Eotaxin-2 / MPIF-2 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL24 / Eotaxin-2 / MPIF-2 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL24; Eotaxin-2; MPIF-2; SCYA24; MPIF2; Ckb-6; MPIF-2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL24 |
| Entrez Gene ID | 6369 |
| Ensemble Gene ID | ENSG00000106178 |
| RefSeq Protein Accession(s) | NP_002982.2 |
| RefSeq mRNA Accession(s) | NM_002991.2, XM_011516459.2, XM_011516460.2 |
| UniProt ID(s) | O00175 |
| UniGene ID(s) | Hs.247838 |
| HGNC ID(s) | HGNC:10623 |
| COSMIC ID Link(s) | CCL24 |
| KEGG Gene ID(s) | hsa:6369 |
| PharmGKB ID(s) | PA35555 |
| General Description of Recombinant Human CCL24 / Eotaxin-2 / MPIF-2 Protein. | |
| Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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