PDF DatasheetMouse CCL12 / MCP-5 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL12 / MCP-5 based upon sequence from: Mouse
Host: QP10271 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Mouse CCL12 / MCP-5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10271.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-50 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Mouse CCL12 / MCP-5 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse CCL12 / MCP-5 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL12; MCP-5; Scya12; MCP-5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Ccl12 |
| Entrez Gene ID | 20293 |
| Ensemble Gene ID | ENSMUSG00000035352 |
| RefSeq Protein Accession(s) | NP_035461.2 |
| RefSeq mRNA Accession(s) | NM_011331.2 |
| UniProt ID(s) | Q62401 |
| UniGene ID(s) | Mm.867 |
| KEGG Gene ID(s) | mmu:20293 |
| General Description of Recombinant Mouse CCL12 / MCP-5 Protein. | |
| Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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