PDF DatasheetHuman IL-1 alpha / IL1A / IL1F1 Protein Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL-1 alpha / IL1A / IL1F1 Protein based upon sequence from: Human
Host: QP10306 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL-1 alpha / IL1A / IL1F1 Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10306.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg/ml, corresponding to a specific activity of > 1.0 × 109 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL-1 alpha / IL1A / IL1F1 Protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein Protein General Information | |
|---|---|
| Alternate Names | |
| IL-1 alpha; IL1A; IL1F1 Protein; IL1; IL1-ALPHA; IL1F1; IL-1A | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL1A |
| Entrez Gene ID | 3552 |
| Ensemble Gene ID | ENSG00000115008 |
| RefSeq Protein Accession(s) | NP_000566.3 |
| RefSeq mRNA Accession(s) | NM_000575.4 |
| UniProt ID(s) | P01583 |
| UniGene ID(s) | Hs.1722 |
| HGNC ID(s) | HGNC:5991 |
| COSMIC ID Link(s) | IL1A |
| KEGG Gene ID(s) | hsa:3552 |
| PharmGKB ID(s) | PA29807 |
| General Description of Recombinant Human IL-1 alpha / IL1A / IL1F1 Protein Protein. | |
| Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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