Human IL2 / Interleukin-2 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL2 / Interleukin-2 based upon sequence from: Human
Host: QP10309 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL2 / Interleukin-2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10309.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL2 / Interleukin-2 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 5.0, lyophilized
Storage Conditions: Store at -20C to -80C.
Recombinant Human IL2 / Interleukin-2 Protein General Information | |
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Alternate Names | |
IL2; Interleukin-2; lymphokine; IL-2; TCGF | |
Curated Database and Bioinformatic Data | |
Gene Symbol | IL2 |
Entrez Gene ID | 3558 |
Ensemble Gene ID | ENSG00000109471 |
RefSeq Protein Accession(s) | NP_000577.2 |
RefSeq mRNA Accession(s) | NM_000586.3 |
UniProt ID(s) | P60568 |
UniGene ID(s) | Hs.89679 |
HGNC ID(s) | HGNC:6001 |
COSMIC ID Link(s) | IL2 |
KEGG Gene ID(s) | hsa:3558 |
PharmGKB ID(s) | PA195 |
General Description of Recombinant Human IL2 / Interleukin-2 Protein. | |
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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