PDF DatasheetHuman IL20 / Interleukin-20 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL20 / Interleukin-20 based upon sequence from: Human
Host: QP10325 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL20 / Interleukin-20, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10325.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human IL-20Ralpha and human IL-20Rbeta co-transfected murine BaF3 pro-B cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 ×106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL20 / Interleukin-20 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.2, with trehalose, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL20 / Interleukin-20 Protein General Information | |
|---|---|
| Alternate Names | |
| IL20; Interleukin-20; IL-20; ZCYTO10; IL10D | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL20 |
| Entrez Gene ID | 50604 |
| Ensemble Gene ID | ENSG00000162891 |
| RefSeq Protein Accession(s) | NP_061194.2 |
| RefSeq mRNA Accession(s) | NM_018724.3 |
| UniProt ID(s) | Q9NYY1 |
| UniGene ID(s) | Hs.272373 |
| HGNC ID(s) | HGNC:6002 |
| COSMIC ID Link(s) | IL20 |
| KEGG Gene ID(s) | hsa:50604 |
| PharmGKB ID(s) | PA29817 |
| General Description of Recombinant Human IL20 / Interleukin-20 Protein. | |
| Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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