PDF DatasheetHuman CD137 / 4-1BB / TNFRSF9 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CD137 / 4-1BB / TNFRSF9 based upon sequence from: Human
Host: QP10333 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CD137 / 4-1BB / TNFRSF9, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10333.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity is determined by its inhibitory effect of IL-8 production using human peripheral blood mononuclear cells. About 90 % of inibition was seen using a concentration of 1 ug for both 4-1BB Ligand and 4-1BB Receptor.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: ERTRSLQDPC SNCPAGTFCD NNRNQICSPC PPNSFSSAGG QRTCDICRQC KGVFRTRKEC SSTSNAECDC TPGFHCLGAG CSMCEQDCKQ GQELTKKGCK DCCFGTFNDQ KRGICRPWTN CSLDGKSVLV NGTKERDVVC GPSPADLSPG ASSVTPPAPA REPGHS
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CD137 / 4-1BB / TNFRSF9 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CD137 / 4-1BB / TNFRSF9 Protein General Information | |
|---|---|
| Alternate Names | |
| CD137; 4-1BB; TNFRSF9; Ly63; AA408498; CDw137; ILA; A930040I11Rik; AI325004; Cd137; 4-1BB | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFRSF9 |
| Entrez Gene ID | 3604 |
| Ensemble Gene ID | ENSG00000049249 |
| RefSeq Protein Accession(s) | NP_001552.2 |
| RefSeq mRNA Accession(s) | NM_001561.5, XM_011541386.2 |
| UniProt ID(s) | Q07011 |
| HGNC ID(s) | HGNC:11924 |
| COSMIC ID Link(s) | TNFRSF9 |
| KEGG Gene ID(s) | hsa:3604 |
| PharmGKB ID(s) | PA36617 |
| General Description of Recombinant Human CD137 / 4-1BB / TNFRSF9 Protein. | |
| Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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