PDF DatasheetHuman 4-1BBL / CD137L / TNFSF9 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant 4-1BBL / CD137L / TNFSF9 based upon sequence from: Human
Host: QP10334 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human 4-1BBL / CD137L / TNFSF9, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10334.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml, corresponding to a specific activity of > 1.0 × 105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE
Purity: Greater than 95% as determined by SDSPAGE and HPLC.
Reconstitution Instructions:
Concentration of Human 4-1BBL / CD137L / TNFSF9 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human 4-1BBL / CD137L / TNFSF9 Protein General Information | |
|---|---|
| Alternate Names | |
| 4-1BBL; CD137L; TNFSF9; 4-1BBL; Cd137l; AI848817; 4-1BB-L; Ly63l | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFSF9 |
| Entrez Gene ID | 8744 |
| Ensemble Gene ID | ENSG00000125657 |
| RefSeq Protein Accession(s) | NP_003802.1 |
| RefSeq mRNA Accession(s) | NM_003811.3 |
| UniProt ID(s) | P41273 |
| UniGene ID(s) | Hs.1524 |
| HGNC ID(s) | HGNC:11939 |
| COSMIC ID Link(s) | TNFSF9 |
| KEGG Gene ID(s) | hsa:8744 |
| PharmGKB ID(s) | PA36629 |
| General Description of Recombinant Human 4-1BBL / CD137L / TNFSF9 Protein. | |
| Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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