PDF DatasheetHuman TNFRSF17 / BCMA Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant TNFRSF17 / BCMA based upon sequence from: Human
Host: QP10365 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human TNFRSF17 / BCMA, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10365.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng/ml, corresponding to a specific activity of > 2.5 × 104 IU/mg in the presence of 100 ng/ml human APRIL.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human TNFRSF17 / BCMA Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 30 % acetonitrile, 0.1 % TFA, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TNFRSF17 / BCMA Protein General Information | |
|---|---|
| Alternate Names | |
| TNFRSF17; BCMA; BCMA; BCM; Tnfrsf13; Tnfrsf13a | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFRSF17 |
| Entrez Gene ID | 608 |
| Ensemble Gene ID | ENSG00000048462 |
| RefSeq Protein Accession(s) | NP_001183.2 |
| RefSeq mRNA Accession(s) | NM_001192.2 |
| UniProt ID(s) | Q02223 |
| HGNC ID(s) | HGNC:11913 |
| COSMIC ID Link(s) | TNFRSF17 |
| KEGG Gene ID(s) | hsa:608 |
| PharmGKB ID(s) | PA36606 |
| General Description of Recombinant Human TNFRSF17 / BCMA Protein. | |
| Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.