PDF DatasheetHuman TNFRSF13B / TACI / CD267 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant TNFRSF13B / TACI / CD267 based upon sequence from: Human
Host: QP10368 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human TNFRSF13B / TACI / CD267, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10368.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity is determined by its ability to block human BAFF induced T2B cell survival using a concentration range of 1.0-3.0 ug/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL PGLKLSADQV
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human TNFRSF13B / TACI / CD267 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TNFRSF13B / TACI / CD267 Protein General Information | |
|---|---|
| Alternate Names | |
| TNFRSF13B; TACI; CD267; CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFRSF13B |
| Entrez Gene ID | 23495 |
| Ensemble Gene ID | ENSG00000240505 |
| RefSeq Protein Accession(s) | NP_036584.1 |
| RefSeq mRNA Accession(s) | NM_012452.2 |
| UniProt ID(s) | O14836 |
| HGNC ID(s) | HGNC:18153 |
| COSMIC ID Link(s) | TNFRSF13B |
| KEGG Gene ID(s) | hsa:23495 |
| PharmGKB ID(s) | PA38509 |
| General Description of Recombinant Human TNFRSF13B / TACI / CD267 Protein. | |
| Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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