PDF DatasheetHuman TL1A / TNFSF15 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant TL1A / TNFSF15 based upon sequence from: Human
Host: QP10372 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human TL1A / TNFSF15, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10372.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to induce apoptosis using human TF-1 cells is less than 20 ng/ml, corresponding to a specific activity of > 5.0 × 104 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV VRQTPTQHFK NQFPALHWEH ELGLAFTKNR MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLL
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human TL1A / TNFSF15 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, with 0.02% Tween-20, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TL1A / TNFSF15 Protein General Information | |
|---|---|
| Alternate Names | |
| TL1A; TNFSF15; TL1A; VEGI192A; VEGI; TNLG1B; TL1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFSF15 |
| Entrez Gene ID | 9966 |
| Ensemble Gene ID | ENSG00000181634 |
| RefSeq Protein Accession(s) | NP_001191273.1 |
| RefSeq mRNA Accession(s) | NM_001204344.1, NM_005118.3 |
| UniProt ID(s) | O95150 |
| HGNC ID(s) | HGNC:11931 |
| COSMIC ID Link(s) | TNFSF15 |
| KEGG Gene ID(s) | hsa:9966 |
| PharmGKB ID(s) | PA36623 |
| General Description of Recombinant Human TL1A / TNFSF15 Protein. | |
| Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.