PDF DatasheetHuman Epiregulin / EREG Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Epiregulin / EREG based upon sequence from: Human
Host: QP10397 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Epiregulin / EREG, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10397.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: VAQVSITKCS SDMNGYCLHG QCIYLVDMSQ NYCRCEVGYT GVRCEHFFL
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Epiregulin / EREG Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Epiregulin / EREG Protein General Information | |
|---|---|
| Alternate Names | |
| Epiregulin; EREG; EPR | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EREG |
| Entrez Gene ID | 2069 |
| Ensemble Gene ID | ENSG00000124882 |
| RefSeq Protein Accession(s) | NP_001423.1 |
| RefSeq mRNA Accession(s) | NM_001432.2 |
| UniProt ID(s) | O14944 |
| UniGene ID(s) | Hs.115263 |
| HGNC ID(s) | HGNC:3443 |
| COSMIC ID Link(s) | EREG |
| KEGG Gene ID(s) | hsa:2069 |
| PharmGKB ID(s) | PA27856 |
| General Description of Recombinant Human Epiregulin / EREG Protein. | |
| Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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